Articles on Dengue
Inhibitory effects of glutathione on dengue virus production.
Tian Y, Jiang W, Gao N, Zhang J, Chen W, Fan D, Zhou D, An J. Department of Histology and Embryology, School of Basic Medicine, Third Military Medical University, Chongqing 400038, PR China.
Reduced glutathione (GSH) is the most powerful intracellular antioxidant and also involved in viral infections. This study investigated the relationship between DV serotype 2 (DV2) infections and host intracellular GSH content. Results showed infection with DV2 resulted in a decrease in intracellular GSH, which caused NF-kappaB activation and increased DV2 production. Supplemental GSH significantly inhibited… Read more.
